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KMID : 0882420110810050592
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Korean Journal of Medicine
2011 Volume.81 No. 5 p.592 ~ p.594
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Clinical Meaning of Incidental Thyroid Uptake on F-18 FDG PET-CT
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Hahm Jong-Ryeal
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Abstract
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Thyroid nodular lesions and thyroiditis are commonly observed in population over thirties. Since the whole-body F18-fluorodeoxyglucose positron emission tomography (PET-CT) system is widely utilized in clinical application, the detection of incidental thyroid uptake has increased significantly. Unexpected thyroid uptake on PET-CT can be divided into three distinguishable patterns: focal, diffuse, or diffuse plus focal. Focal uptake, incidentaloma, is clinically significant because of its high risk of malignancy at the range of 25-50%. Therefore, the cytologic diagnosis should be additionally performed in these patients. Diffuse pattern of thyroid uptake is very likely secondary to thyroiditis and/or hypothyroidism. Although the clinical meaning of diffuse plus focal uptake of thyroid observed on PET-CT is not clear, the risk of malignancy was increased when it compared with diffuse uptake pattern only. However, further evaluation is required to define its clinical significance.
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KEYWORD
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18F-FDG, Thyroiditis, Incidentaloma
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